Dawson Creek RCMP respond to complaint of male brandishing a handgun

first_imgAround noon today Dawson Creek RCMP responded to a complaint of a male brandishing a handgun in the area of 10 Street and 104 Avenue. Given the location Central Middle School was locked down because of the situation.Officers established a perimeter around the area but no suspect was located.A description of the suspect is said to have been minimal. As such Dawson Creek RCMP are asking the public if anyone was in the area at that time and had seen anything to contact them at 250-784-3700.- Advertisement –last_img read more

DONEGAL VOTES YES – AND THAT’S OFFICIAL!

first_imgThe Yes campaign celebrate at the count centre in Bonagee.Donegal has said Yes!Both Donegal North East and South West has voted ‘yes’ in the Marriage Equality Referendum.The announcement was made just a short time ago by Donegal NE returning officer Geraldine O’Connor at the Bonagee Community Centre outside Letterkenny.There were shouts of joy as the result was finally read out.The electorate was 59,721 with the amount of those who voted was 30,723.The total invalid vote was 191.The total valid poll was 30,532 with 16,040 voting yes while 14,492 voted no.There were just 33 votes in the different in Donegal South West however.There was talk of a recount but this has ben discounted because the rest of the country had turned a yes vote.A total of 15,907 voted yes while 15,874 voted no. DONEGAL VOTES YES – AND THAT’S OFFICIAL! was last modified: May 24th, 2015 by StephenShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window)last_img read more

Burnley v Fulham line-ups: Whites keeper misses out, Clarets unchanged

first_imgGoalkeeper Andy Lonergan misses out on Fulham’s trip to Burnley, with Joe Lewis replacing him.It is the only change from the 4-1 win at Bristol City, with Moussa Dembele retaining his place up front after five goals in his last three games.Matt Smith is once again on a very strong bench, alongside the likes of Luke Garbutt, Ben Pringle, Lasse Christensen, Cauley Woodrow and Alex Kacankilic.Burnley, who like Fulham are unbeaten in their last five matches, name an unchanged side from the one which beat Huddersfield on Saturday.It means former QPR midfielder Joey Barton and ex-Brentford striker Andre Gray start, with one-time Bees loanee Chris Long among the substitutes.Burnley: Heaton; Darikwa, Duff, Keane, Mee; Boyd, Jones, Barton, Arfield; Vokes, Gray. Subs: Gilks, Ward, Ulvestad, Taylor, Lowton, Long, Hennings.Fulham: Lonergan; Burn, Stearman, Ream, Husband; Tunnicliffe, Cairney; Fredericks, McCormack, O’Hara; Dembele. Subs: Rodak, Garbutt, Pringle, Christensen, Kacaniklic, Woodrow, Smith.Follow West London Sport on TwitterFind us on Facebooklast_img read more

Molecular Machines Under the Nanoscope

first_imgThe second two articles did not discuss how these mechanisms could have evolved.  Indeed, it would be a challenge to think of a scenario how they could evolve, since life at the most basic, primitive level depends on the activity of these specialized enzymes.1Rajagopala et al, “The protein network of bacterial motility,” Nature: Molecular Systems Biology 3 Article number: 128 doi:10.1038/msb4100166.2Gledhill, Montgomery, Leslie and Walker, “How the regulatory protein, IF1, inhibits F1-ATPase from bovine mitochondria,” Proceedings of the National Academy of Sciences USA, published online before print September 25, 2007, Proc. Natl. Acad. Sci. USA, 10.1073/pnas.0707326104.3Ghosh and Vishveshwara, “A study of communication pathways in methionyl-tRNA synthetase by molecular dynamics simulations and structure network analysis,” Proceedings of the National Academy of Sciences USA, published online before print September 26, 2007, Proc. Natl. Acad. Sci. USA, 10.1073/pnas.0704459104.Let the evolutionists speculate and spin their webs of belief; we have the observational evidence in front of our noses that shout design.  The precision of fit of these parts, and the accuracy of their performance, is beyond any theory of chance and blind stumbling in the dark.  We do not accept the circular reasoning of the Darwinists who keep saying they evolved because they have a phylogenetic tree, and they have a phylogenetic tree because they evolved.  Those dependent clauses collapse in on themselves.  Neither do we accept the merry-go-round reasoning that says they are wonderfully adapted because they evolved, and they must have evolved because they are wonderfully adapted.  No more Darwinian rhetorical tricks.  Look, behold, wonder, and use your God-given common sense.(Visited 11 times, 1 visits today)FacebookTwitterPinterestSave分享0 Seeing machines just billionths of a meter long seems impossible, but cell biologists are now routinely looking into the cellular black box.  Using indirect but powerful methods, they can actually begin to visualize the gears and wheels and cogs of the protein machines that make life possible.  Some of our favorite cell gadgets were examined in recent papers.Bacterial flagellum:  A paper in Nature: Molecular Systems Biology1 juxtaposed design language with evolutionary speculation.  Rajagopala et al began with high praise for the Ferrari of the cellular world:Motility in most bacterial species depends on a sophisticated molecular machine called the flagellum.  The flagellar apparatus is made of dozens of different proteins and thousands of individual subunits.  The bacterial flagellum is actually a mechanical nanomachine with a rotation frequency of 300 Hz, an energy conversion rate of nearly 100%, and the ability to self assemble.So far this sounds like Michael Behe’s writing.  Indeed, these authors representing three countries found even more essential protein parts for the flagellum – take one away, in other words, and motion stops.  But the gist of their paper was that the variety of flagella in different species shows evolution: “Many features of the bacterial flagellum have changed over the course of evolution,” they said.  “This is reflected in the surprisingly different composition and protein interaction patterns in the flagella of different species, which may reflect adaptations to species-specific motility needs.”    Yet their argument was based entirely on homology.  They did not explain how needs produced functional, adapting flagella.  They merely built an evolutionary tree based on similarities:The bacterial flagellum represents an interesting entity to study the evolution of complex biological machines.  For an evolutionary view of the flagellum on the protein level, we constructed a phylogenetic supertree solely based on flagellar protein sequences.  As anticipated, this tree closely recapitulates phylogenetic relationships identified, employing traditional phylogenetic marker molecules such as rRNAs.    Whereas it is generally believed that the motility machinery evolved from an ancient type III secretion system, the detailed steps leading to current structures have yet to be defined….    Similar to protein sequences and structures, interactions among proteins are often conserved in the course of evolution.  In fact, the phylogenetic relationships of different species are partially reflected by the phylogenetic interaction profile of the integrated network.Conservation is not evolution.  Phylogenetic tree construction, furthermore, presumes the very question under investigation: that flagella evolved in the first place.  And as any creationist would say, adaptation is not proof of evolution; it is proof of design.    In summary, these authors could not help but marvel at the flagellum.  They found an even more amazing network of interactions among the conserved protein parts.  Their conclusions about evolution, however, were based only on arguably circular arguments from homology.  Indeed, “the detailed steps leading to current structures have yet to be defined” in their own article.ATP Synthase:  A team of UK scientists publishing in PNAS investigated one detail of the other sophisticated rotary motor in all of life: ATP synthase.2 (See 09/18/2003, 07/16/2002.)  They wanted to know how a regulatory protein named IF1 inhibits the motor, like a Denver boot.  (After all, a high-performance motor usually comes with brakes.)  Stopping a spinning motor is not a simple matter.  They found it takes a complex set of protein interactions that forms an “inhibitory complex” with the machine like – well, let them explain:To form these complex interactions and penetrate into the core of the enzyme, it is likely that the initial interaction of the inhibitor with F1 forms via the open conformation of the {beta}E subunit.  Then, as two ATP molecules are hydrolyzed, the {beta}E-{alpha}E interface converts to the {beta}DP-{alpha}DP interface via the {beta}TP-{alpha}TP interface, trapping the inhibitor progressively in its binding site and a nucleotide in the catalytic site of subunit {beta}DP.  The inhibition probably arises by IF1 imposing the structure and properties of the {beta}TP-{alpha}TP interface on the {beta}DP-{alpha}DP interface, thereby preventing it from hydrolyzing the bound ATP.Transfer RNA:  One of the most amazing sets of machines, on which all forms of life depend, is the crew of translators that know which amino acid goes with which codon from the DNA code.  A family of 20 of these molecules, known as aminoacyl-tRNA synthetases, or aaRS for short, exists – one for each amino acid.  Each one knows its own amino acid and tRNA so well the accuracy of their operation is stunning.  Even when there are cognate codons (three-letter codes that differ yet code for the same amino acid), the machines rarely make a mistake.  For instance, metRS, the synthetase for methionine, can match two cognate codons with the right amino acid every time and eject very similar ones.    Herein lies a mystery: if you look at a tRNA molecule (which looks something like a letter t), and the synthetase that works on it, the two active sites are separated by some distance.  The anticodon on the tRNA is on the bottom of the “t”, but the amino acid binding site is at the other end – a whopping seven nanometers away.  Seven nanometers may not sound like a lot, but at the molecular scale, that’s a lot.  How does one end of a blind machine communicate with the other end?    To find out, two Indian researchers investigated metRS in detail and published their results in PNAS.3  They found that vibrations ripple through the amino acids of the enzyme along four pathways.  The strongest one overrules the others when the twist is just right.  Furthermore, they found that these communications caused conformational changes – swings like a lever arm, flips and turns – that had to match the substrate in order to work.  The amino acid would only attach if all the contact points were just right:Furthermore, the network analysis on these simulated structures has been carried out to elucidate the paths of communication between the activation site and the anticodon recognition site.  This study has provided the detailed paths of communication, which are consistent with experimental results…. A comparison of the paths derived from the four simulations clearly has shown that the communication path is strongly correlated and unique to the enzyme complex, which is bound to both the tRNA and the activated methionine.last_img read more

‘Partnership needed to lift economy’

first_img15 October 2012A robust partnership between the government, business and labour is needed to address the economic challenges facing South Africa, says President Jacob Zuma.“There is a need to work together on our economy … which has also faced pressure due to the current wave of strikes,” Zuma said at a social dialogue meeting between government, business and labour representatives in Pretoria on Friday.“We reiterate our call to business and labour to work together to find solutions, so that we can revert to the primary task at hand – to build the country, build the economy and improve the quality of life.“We need to create the right climate, environment and ideas to develop our economy,” Zuma said. “Urgent steps are needed to avoid an economic downturn.”Measures to stimulate economic growthHe encouraged stakeholders to come up with new measures to stimulate economic growth.The government recently adopted a massive infrastructure plan that is expected to transform the country’s economic landscape and strengthen the delivery of basic services to the population.“We have various other packages to boost manufacturing and to support job creation in general … There is a lot that we can do, and we need those ideas today so that we can develop a workable framework,” Zuma said.“We need a partnership based on clear commitments and actions by each of us. We have begun to do some work on what government can do… but we cannot succeed if we rely only on government. We need a joint response. That is why we have assembled this leadership team here today.”Call for end to violence in strikesThe meeting, which was attended by the ministers from the economic and security clusters, also included the presidents of Business Unity South Africa, the Black Business Council, labour organisations Cosatu, Fedusa, Nactu, and Nedlac’s top brass.Although the leaders welcomed the end of the three-week truck drivers’ strike and efforts to resolve the strikes in the platinum, gold and coal mining industries, they expressed grave concern over the lawlessness and the escalation of violent strikes in some sectors.They called on the law enforcement agencies to act firmly against these elements, pledging their cooperation in talks to end strikes in the mining industry.Speaking at the end of the meeting, Performance Monitoring and Evaluation Minister Collins Chabane said the parties agreed that there was a need to speed up the fight against poverty, inequality and unemployment in the country.“The parties agreed to take steps to improve public and investor confidence in the economy and to promote social stability using their respective resources and capacities to build a partnership for development,” he said.Concerning Marikana, the parties agreed to support the commission of inquiry and urged people to participate freely in the commission. They said law enforcement agencies had to assist in ensuring the right environment for people to participate, with the support of the community.Source: SANews.gov.zalast_img read more

Ticketing hassles keep spectators away from Commonwealth Games

first_imgThe Commonwealth Games got off to a scintillating opening three days ago but a tight security apparatus, far-away venues and several ticketing issues are still keeping spectators away from the mega sporting event.While empty stadiums are giving sleepless nights to Games organisers, spectators complain that procuring a ticket itself is a big problem and once they get one, reaching the venues offers more challenges.The Organising Committee has set up ticket booths outside venues after the intervention of the Games Federation which was clearly unhappy with the poor attendance at the stadiums.Spectators complain that reaching the venues were a big problem due to traffic restrictions.”One has to walk a long distance in sun, may be three kilometres or more, to reach the venues. You have to park your vehicle some five-seven kilometres away. It is hell reaching a stadium,” said Sushil Das, who went to Yamuna Sports Complex.Another concern of the spectators was the “unnecessary” security restrictions.”It was very hard for me to convince the policemen at the access point that I will not harm anyone with my car keys.They kept saying they cannot allow me inside with car keys.This is ridiculous,” said Ranjan Saxena, who visited the Indira Gandhi stadium.A senior Organising Committee official said security apparatus apparently was turning away spectators from the stadiums.People also complained about long queues at ticket counters and the time taken for giving tickets.”It is not rocket science. One should get a ticket in minutes after the payment is done. Here one has to wait for more than 15 minutes sometimes,” Anjana Shukla, who went to Indira Gandhi stadium, said.advertisementAnother problem was the “high-priced” food at the venues.”We are not allowed to take food. The prices are very high at the venues. Who can afford this?” asked Dipak Gupta, a spectator.However, spectators were more livid at the security arrangements for the event. “Police comes up with new instructions everyday. I have to part with coins when it is not in the list of prohibited items,” said a spectator.In one case, wife of noted writer William Dalrymple claimed that she lost all “barred items” which was kept by police personnel at the R K Khanna Stadium where she had gone to watch tennis match. Delhi Police however said they have not received any such complaints.last_img read more

10 months agoMan City ace Gabriel Jesus: I’m learning a lot from Aguero

first_imgAbout the authorPaul VegasShare the loveHave your say Man City ace Gabriel Jesus: I’m learning a lot from Agueroby Paul Vegas10 months agoSend to a friendShare the loveManchester City ace Gabriel Jesus admits he’s enjoying working alongside Sergio Aguero.The Brazilian’s lack of goals was partly down to limited game-time caused by the impressive form of his fellow South American Aguero.City’s all-time leading goalscorer recently missed three games with a groin injury, but City will expect to benefit from having both forwards healthy and in form.”Sergio is a good guy,” Gabriel said.”I like him. I like his football. He is a legend for City and I’m learning a lot from him.” last_img read more

Photo: A Duke Fan Gets A New Custom License Plate Every Time The Blue Devils Win A National Title

first_imgDuke fans get riled up for a game.DURHAM, NC – FEBRUARY 09: Cameron Crazies, fans of the Duke Blue Devils, prepare for their game against the North Carolina Tar Heels at Cameron Indoor Stadium on February 9, 2017 in Durham, North Carolina. (Photo by Streeter Lecka/Getty Images)When Duke’s men’s basketball program won its fifth national championship under Mike Krzyzewski this past spring, it was time for the following car to get a new license plate. The driver of this Subaru Outback gets a new custom license plate every time the Blue Devils win a national title. Here they are: # 5 and Kounting pic.twitter.com/HoNr1uOVm6— Brad Allen Cleary (@bacduke_hoops) June 7, 2015Are all of the license plates kept on the car or were they just being shown off together? Either way, it’s an impressive collection.last_img read more

Former Cincinnati Player Says Butch Jones Hit Players At Practice “Multiple Times”

first_imgJohn Lloyd tweets that Butch Jones hit players at practice.john lloyd cincinnati butch jonesLast week, a number of rumors regarding Tennessee head coach Butch Jones – including a claim that he punched a player this past summer during practice – made the rounds on social media. This Monday, Jones commented on the rumor, calling it “absolutely ridiculous.” Wednesday night, one of Jones’ former players made an interesting claim on Twitter regarding the situation.Former Cincinnati punter John Lloyd, who played for Jones from 2010-2012, told his followers that he saw Jones hit players “multiple times” during his time with the Bearcats. He also joked that Jones “probably” made Cincinnati’s video crew delete practice footage. It wasn’t a glowing review of his former [email protected] here are the tweets. pic.twitter.com/cFj2LkDLLn— Football Time in TN (@FootballTimeMag) October 8, 2015Lloyd has since deleted the tweets and moved his account to private, for what it’s worth. Despite Jones’ statement on the matter, it doesn’t seem that this story has gone away. We’ll keep you updated.last_img read more

Video: USC WR JuJu Smith-Schuster Tossed A Utah Defender With A Nasty Stiff-Arm

first_imgA general view of the Los Angeles Memorial Coliseum.LOS ANGELES – NOVEMBER 11: General view of action as the Oregon Ducks take on the USC Trojans on November 11, 2006 at the Los Angeles Memorial Coliseum in Los Angeles, California. The Trojans defeated the Ducks 35-10. (Photo by Christian Petersen/Getty Images)USC knocked Utah from the ranks of the unbeaten with a 42-24 victory tonight. During the win, USC wide receiver JuJu Smith-Schuster knocked a Utah defender clear out of the field of play with a nasty stiff-arm. It’s been speculated that Smith-Schuster was pointing at the defender to call him out to come get stiff-armed, but it looks like he was just trying to signal for more downfield blocking. Nasty play though.last_img read more